ChemicalBook >> CAS DataBase List >>4'-Methyl-2-cyanobiphenyl
4'-Methyl-2-cyanobiphenyl
- CAS No.
- 114772-53-1
- Chemical Name:
- 4'-Methyl-2-cyanobiphenyl
- Synonyms
- OTBN;2-Cyano-4'-methylbiphenyl;2MPPC;AKOS BAR-1203;Sartandiphenyl;Sartanbiphenyl;methyl diphenyl;-2-cyanobiphenyL;2-tolylbenzonitrile;2-hexylbenzonitrile
- CBNumber:
- CB7337004
- Molecular Formula:
- C14H11N
- Molecular Weight:
- 193.24
- MDL Number:
- MFCD00151805
- MOL File:
- 114772-53-1.mol
- MSDS File:
- SDS
Last updated:2024-07-29 18:03:56
| Melting point | 49 °C |
|---|---|
| Boiling point | >320°C |
| Density | 1,17 g/cm3 |
| vapor pressure | 0.014Pa at 20℃ |
| Flash point | >320°C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| color | Off-white to beige |
| BRN | 3605954 |
| InChI | InChI=1S/C14H11N/c1-11-6-8-12(9-7-11)14-5-3-2-4-13(14)10-15/h2-9H,1H3 |
| InChIKey | ZGQVZLSNEBEHFN-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=C(C)C=C2)=CC=CC=C1C#N |
| LogP | 3.5 at 23℃ |
| CAS DataBase Reference | 114772-53-1(CAS DataBase Reference) |
| FDA UNII | O417TI15TA |
| NIST Chemistry Reference | Benzonitrile, 2-(4-methylphenyl)-(114772-53-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H302-H312-H332-H313-H361-H372-H401-H411 | |||||||||
| Precautionary statements | P280-P201-P260-P301+P312a-P405-P501a-P261-P264-P270-P271-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38-48/25/62/51/53-22 | |||||||||
| Safety Statements | 22-26-36/37/39-36/37/45/57-20-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 27075000 | |||||||||
| NFPA 704 |
|
4'-Methyl-2-cyanobiphenyl price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C1446 | 2-Cyano-4'-methylbiphenyl >99.0%(GC) | 114772-53-1 | 10g | $37 | 2024-03-01 | Buy |
| Alfa Aesar | B21273 | 2-Cyano-4'-methylbiphenyl, 98+% | 114772-53-1 | 5g | $50.8 | 2024-03-01 | Buy |
| Alfa Aesar | B21273 | 2-Cyano-4'-methylbiphenyl, 98+% | 114772-53-1 | 25g | $162 | 2024-03-01 | Buy |
| Alfa Aesar | B21273 | 2-Cyano-4'-methylbiphenyl, 98+% | 114772-53-1 | 100g | $431 | 2024-03-01 | Buy |
| TRC | M294115 | 4''-Methylbiphenyl-2-carbonitrile | 114772-53-1 | 25g | $185 | 2021-12-16 | Buy |
4'-Methyl-2-cyanobiphenyl Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Uses
4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.
Synthesis
4'-Methyl-2-cyanobiphenyl is prepared by the reaction of o-cyanobromobenzene and potassium (4-methylphenyl)trifluoroborate. The specific synthesis steps are as follows:
General procedure: A mixture of aryl halide (0.5 mmol), potassium aryltrifluoroborate (0.6 mmol), K2CO3 (1.0 mmol), Pd/C (5%; 0.5 mol%), ethanol (3 mL), and distilled water (1 mL) was stirred at 80 °C in air for the time indicated.
The reaction mixture was added to brine (15 mL) and extracted with ethyl acetate (4×15 mL).
The organic solvent was removed under vacuum, and the product was isolated by short-column chromatography.
4'-Methyl-2-cyanobiphenyl Preparation Products And Raw materials
Global( 643)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JUYE XIANDAI fine chemistry Co.,Ltd | +86-18958038633; +8618958038633 | tony@sdhypharma.com | China | 64 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +86-19930503253; +8619930503252 | daisy@crovellbio.com | China | 5835 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20297 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@airuikechemical.com | China | 983 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16854 | 58 |
| Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 | sales@richfortunechem.com | China | 304 | 57 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21669 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9337 | 55 |
View Lastest Price from 4'-Methyl-2-cyanobiphenyl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-08-07 | 4'-Methyl-2-cyanobiphenyl
114772-53-1
|
US $0.00 / KG | 1KG | 99% | 200mt | Jinan Finer Chemical Co., Ltd | |
 |
2024-07-29 | 4'-Methyl-2-cyanobiphenyl
114772-53-1
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD | |
 |
2024-04-24 | 4'-Methyl-2-cyanobiphenyl
114772-53-1
|
US $1.00 / KG | 1KG | 99.91% | 200000 | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- 4'-Methyl-2-cyanobiphenyl
114772-53-1
- US $0.00 / KG
- 99%
- Jinan Finer Chemical Co., Ltd
-
- 4'-Methyl-2-cyanobiphenyl
114772-53-1
- US $5.00-2.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- 4'-Methyl-2-cyanobiphenyl
114772-53-1
- US $1.00 / KG
- 99.91%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
114772-53-1(4'-Methyl-2-cyanobiphenyl)Related Search:
2-cyanogen radical-4'-methyl biphenyl
2-[(4-methyl)pentyl]-benzonitrile
4'-Methyl-2-Cyano Diphenyl
AKOS BAR-1203
4'-METHYLBIPHENYL-2-CARBONITRILE
4'-METHYL-2-BIPHENYLCARBONITRILE
4'-METHYL-2-CYANOBIPHENYL
4'-METHYL[1,1'-BIPHENYL]-2-CARBONITRILE
2-(4-TOLYL)-BENZONITRILE
2-(4-METHYLPHENYL)BENZONITRILE
[2-(P-TOLYL)BENZONITRILE]
2-cyano-4methylbiphenyl 4'-Methylbiphenyl-2-carbonitrile
2-CYANO-4''-METHYLBIPHENYL (OTBN)
4''-METHYL-2-CYANO-BIPHENYL (FOR LOSARTAN)
2-CYANO-4''-METHYLBIPHENYL(SARTANBIPHENYL)
2-tolylbenzonitrile
2-CYANO-4''-METHYLBIPHENYL 99%MIN
Sartandiphenyl
4-Cyanomethylbiphenyl
OTBN (O-Tolybenzenitrile)
Sartanbiphenyl
o-(p-Tolyl)benzonitrile
4'-Methyl-2-cyanobiphenyl,98%
2-(4-Methylphenyl)benzenecarbonitrile
2MPPC
4'-Methyl-2-cyanobipheny
4'-Methyl-2-cyanobip
4'-Methyl-2-cyanobiphenyl ( OTBN )
diethyl 3-(3-acetyl-6-nitro-9H-carbazol-9-yl)propylphosphonate
[1,1'-Biphenyl]-2-carbonitrile, 4'-Methyl-
4'-Methyl-2-cyanobiphenyl SynonyMs 4'-Methylbiphenyl-2-carbonitrile
methyl diphenyl
2-hexylbenzonitrile
Telmisartan Impurity 15
2-Cyano-4'-methylbiphenyl >
2-methyl-2-cyanobiphenyl
-2-cyanobiphenyL
OTBN
4’-Methyl-2-Cyano-Biphenyl
4'-Methyl-2-cyanobiphenyl ISO 9001：2015 REACH
OTBN
2-Cyano-4'-methylbiphenyl
Ortho Tolyl Benzonitrile (OTBN)
4'-methyl-[1,1'-biphenyl]-2-carbonitrile
4'-Methyl-2-cyanobiphenyl
2-Cyano-4-Methyl Bipheny| (OTBN)
114772-53-1
114772-53-21
114772-83-1
14772-53-1
CH3C6H4C6H4CN
Biphenyl & Diphenyl ether
(intermediate of telmisartan)
(intermediate of sartan)
(intermediate of sartan s product)
Losartan Potassium
Biphenyl derivatives
INTERMEDIATESOF
Starting Raw Materials & Intermediates